Grid2^tm1(cre)Mwa
Targeted Allele Detail

Summary

• Symbol: Grid2^tm1(cre)Mwa
• Name: glutamate receptor, ionotropic, delta 2; targeted mutation 1, Masahiko Watanabe
• MGI ID: MGI:4949272
• Synonyms: D2CreN, GluD2^Cre, Grid2^Cre
• Gene: Grid2 Location: Chr6:63232860-64681307 bp, + strand Genetic Position: Chr6, 29.77 cM
• Alliance: Grid2^tm1(cre)Mwa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:170673
• Parent Cell Line: RENKA (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Null/knockout, Recombinase)
• Mutation: Insertion
• Grid2^tm1(cre)Mwa expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Grid2 (MGI:95813)

• The cre sequence and an FRT-flanked neo cassette were inserted at the start codon. (J:170673)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Grid2 (mouse) Summary of all recombinase alleles driven by Grid2. Alliance mouse Grid2 gene page

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Grid2 Mutation: 85 strains or lines available

References

• Original: J:170673 Yamasaki M, et al., Glutamate receptor delta2 is essential for input pathway-dependent regulation of synaptic AMPAR contents in cerebellar Purkinje cells. J Neurosci. 2011 Mar 2;31(9):3362-74
• All: 14 reference(s)