Resp18^tm1Mlit
Targeted Allele Detail

Summary

• Symbol: Resp18^tm1Mlit
• Name: regulated endocrine-specific protein 18; targeted mutation 1, Jian Fei
• MGI ID: MGI:4949626
• Gene: Resp18 Location: Chr1:75248843-75255059 bp, - strand Genetic Position: Chr1, 38.65 cM
• Alliance: Resp18^tm1Mlit page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171182
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The open reading frame was replaced by a neo cassette. A 50% reduction in protein expression was confirmed by western blot analysis on heterozygous brain extracts. (J:171182)

Expression

In Mice Carrying this Mutation:

1 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Resp18 Mutation: 17 strains or lines available

References

• Original: J:171182 Liang M, et al., Requirement of regulated endocrine-specific protein-18 for development and expression of regulated endocrine-specific protein-18 isoform c in mice. Mol Biol Rep. 2011 Apr;38(4):2557-62
• All: 2 reference(s)