Tnfrsf13c^tm2.1Mass
Targeted Allele Detail

Summary

• Symbol: Tnfrsf13c^tm2.1Mass
• Name: tumor necrosis factor receptor superfamily, member 13c; targeted mutation 2.1, Marc Schmidt-Supprian
• MGI ID: MGI:4949656
• Synonyms: BAFF-R^FL
• Gene: Tnfrsf13c Location: Chr15:82105944-82108570 bp, - strand Genetic Position: Chr15, 38.56 cM
• Alliance: Tnfrsf13c^tm2.1Mass page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:92732
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP was inserted upstream of exon 3. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 4. Flp-mediated recombination removed the neo cassette. (J:92732)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tnfrsf13c Mutation: 15 strains or lines available

References

• Original: J:92732 Sasaki Y, et al., TNF family member B cell-activating factor (BAFF) receptor-dependent and -independent roles for BAFF in B cell physiology. J Immunol. 2004 Aug 15;173(4):2245-52
• All: 2 reference(s)