Hoxb4^tm1.1Mev
Targeted Allele Detail

Summary

• Symbol: Hoxb4^tm1.1Mev
• Name: homeobox B4; targeted mutation 1.1, Alexander Medvinsky
• MGI ID: MGI:4949668
• Synonyms: Hoxb4^YFP
• Gene: Hoxb4 Location: Chr11:96209093-96212464 bp, + strand Genetic Position: Chr11, 59.83 cM
• Alliance: Hoxb4^tm1.1Mev page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:170503
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: YFP and an FRT-flanked EM7-blasticidin selection marker cassette were inserted upstream of exon 1. Flp-mediated recombination removed the selection cassette. (J:170503)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxb4 Mutation: 20 strains or lines available

Notes

ES cell line = CGR14 (129/Sv)

References

• Original: J:170503 Hills D, et al., Hoxb4-YFP reporter mouse model: a novel tool for tracking HSC development and studying the role of Hoxb4 in hematopoiesis. Blood. 2011 Mar 31;117(13):3521-8
• All: 1 reference(s)