Pglyrp1^tm1.1Lky
Targeted Allele Detail

Summary

• Symbol: Pglyrp1^tm1.1Lky
• Name: peptidoglycan recognition protein 1; targeted mutation 1.1, Richard M Locksley
• MGI ID: MGI:4949894
• Synonyms: PGRP-S
• Gene: Pglyrp1 Location: Chr7:18618615-18624363 bp, + strand Genetic Position: Chr7, 9.38 cM, cytoband A3
• Alliance: Pglyrp1^tm1.1Lky page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171412
• Parent Cell Line: PC3 (ES Cell)
• Strain of Origin: 129S4/SvJae-Tg(Prm-cre)70Og

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting vector was designed to insert an enhanced yellow fluorescent protein (EYFP), followed by a floxed neomycin (neo) resistance cassette, immediately downstream from the initiation sequence of the peptidoglycan recognition protein, 1 (Pglyrp1) gene. Cre-mediated recombination removed the neo cassette. (J:171412)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pglyrp1 Mutation: 15 strains or lines available

References

• Original: J:171412 Locksley RM, Direct Data Submission 2011/05/10. MGI Direct Data Submission. 2011
• All: 2 reference(s)