Fgfbp3^tm1Tohe
Targeted Allele Detail

Summary

• Symbol: Fgfbp3^tm1Tohe
• Name: fibroblast growth factor binding protein 3; targeted mutation 1, Toshio Heike
• MGI ID: MGI:4949899
• Synonyms: fgf-bp3^lacZ
• Gene: Fgfbp3 Location: Chr19:36894950-36896999 bp, - strand Genetic Position: Chr19, 32.01 cM
• Alliance: Fgfbp3^tm1Tohe page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171305
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A lacZ and neo cassette replaced the coding region in exon 2. The absence of transcript expression is confirmed by RT-PCR analysis on brain extracts. (J:171305)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Fgfbp3 Mutation: 18 strains or lines available

References

• Original: J:171305 Yamanaka Y, et al., Inactivation of fibroblast growth factor binding protein 3 causes anxiety-related behaviors. Mol Cell Neurosci. 2011 Jan;46(1):200-12
• All: 1 reference(s)