Crisp4tm1.2Mkob
Targeted Allele Detail
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Symbol: |
Crisp4tm1.2Mkob |
Name: |
cysteine-rich secretory protein 4; targeted mutation 1.2, Moira K O'Bryan |
MGI ID: |
MGI:4950060 |
Gene: |
Crisp4 Location: Chr1:18185415-18216126 bp, - strand Genetic Position: Chr1, 5.65 cM, cytoband A4
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Alliance: |
Crisp4tm1.2Mkob page
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Germline Transmission: |
Earliest citation of germline transmission:
J:171346
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
C57BL/6
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A loxP site was inserted into intron 2 and a floxed neo cassette was inserted into intro 3 via homologous recombination. Cre mediated recombination removed the neo cassette and exon 3. Western blot and immunohistochemical analysis confirmed the absence of protein expression in epididymides from homozygous mice.
(J:171346)
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Generation of the Crisp4tm1.1Mkob and Crisp4tm1.2Mkob alleles |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Crisp4 Mutation: |
21 strains or lines available
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Original: |
J:171346 Gibbs GM, et al., Cysteine-rich secretory protein 4 is an inhibitor of transient receptor potential M8 with a role in establishing sperm function. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):7034-9 |
All: |
1 reference(s) |
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