Nxf3^tm1.2Jw
Targeted Allele Detail

Summary

• Symbol: Nxf3^tm1.2Jw
• Name: nuclear RNA export factor 3; targeted mutation 1.2, Jeremy Wang
• MGI ID: MGI:4950383
• Gene: Nxf3 Location: ChrX:134972848-134986004 bp, - strand Genetic Position: ChrX, 57.38 cM
• Alliance: Nxf3^tm1.2Jw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171521
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: Cre-mediated recombination removed exons 2 through 8. The absence of protein expression as confirmed by western blot analysis on testes extracts. (J:171521)

Generation of the Nxf3^tm1.1Jw and Nxf3^tm1.2Jw alleles

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nxf3 Mutation: 8 strains or lines available

References

• Original: J:171521 Zhou J, et al., Nxf3 is expressed in Sertoli cells, but is dispensable for spermatogenesis. Mol Reprod Dev. 2011 Apr;78(4):241-9
• All: 1 reference(s)