Xisttm5.2Nbd
Targeted Allele Detail
|
Symbol: |
Xisttm5.2Nbd |
Name: |
inactive X specific transcripts; targeted mutation 5.2, Neil Brockdorff |
MGI ID: |
MGI:4950441 |
Synonyms: |
XistINV |
Gene: |
Xist Location: ChrX:102503979-102526839 bp, - strand Genetic Position: ChrX, 46.15 cM, cytoband D
|
Alliance: |
Xisttm5.2Nbd page
|
|
Germline Transmission: |
Earliest citation of germline transmission:
J:171502
|
Parent Cell Line: |
Not Specified (ES Cell)
|
Strain of Origin: |
129P2/OlaHsd
|
|
Allele Type: |
|
Targeted (Hypomorph) |
Mutations: |
|
Insertion, Intragenic deletion, Inversion
|
|
|
Xisttm5.2Nbd involves 1 genes/genome features (Xist)
View all
|
|
|
Mutation details: A floxed neo cassette was inserted into exon 1 in ES cells containing Xisttm4.1Nbd, which lacks exon 4. Cre-mediated recombination removed the neo cassette and inverts the sequence between the loxP site (including exon 3, exon 2, and the 3' portion of exon 1).
(J:171502)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any Xist Mutation: |
8 strains or lines available
|
|
Original: |
J:171502 Senner CE, et al., Disruption of a conserved region of Xist exon 1 impairs Xist RNA localisation and X-linked gene silencing during random and imprinted X chromosome inactivation. Development. 2011 Apr;138(8):1541-50 |
All: |
1 reference(s) |
|