Rnf168^{Gt(405F11)Cmhd}
Gene trapped Allele Detail

Summary

• Symbol: Rnf168^{Gt(405F11)Cmhd}
• Name: ring finger protein 168; gene trap 405F11, Centre for Modeling Human Disease
• MGI ID: MGI:4962718
• Gene: Rnf168 Location: Chr16:32096277-32120252 bp, + strand Genetic Position: Chr16, 22.51 cM, cytoband B2
• Alliance: Rnf168^{Gt(405F11)Cmhd} page

Mutation origin

• Mutant Cell Line: 405F11
• Germline Transmission: Earliest citation of germline transmission: J:198260
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: GepNMDi3
• Mutation details: The gene trap vector inserted upstream of exon 6. Western blot analysis confirmed the absence of protein expression in the mouse embryonic fibroblasts and splenocytes. (J:198260)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  CMHD-GT_405F11-3	ER895397 ; (MGI Seq Detail)	3' RACE	Chr16:32117205-32117256 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  32 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Disease models

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Rnf168^{Gt(405F11)Cmhd}

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rnf168 Mutation: 74 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 2 reference(s)