Il17b^{Gt(371C12)Cmhd}
Gene trapped Allele Detail

Summary

• Symbol: Il17b^{Gt(371C12)Cmhd}
• Name: interleukin 17B; gene trap 371C12, Centre for Modeling Human Disease
• MGI ID: MGI:4965521
• Gene: Il17b Location: Chr18:61821006-61825609 bp, + strand Genetic Position: Chr18, 34.67 cM, cytoband D3
• Alliance: Il17b^{Gt(371C12)Cmhd} page

Mutation origin

• Mutant Cell Line: 371C12
• Germline Transmission: Earliest citation of germline transmission: J:229778
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Gene trapped (Hypomorph)
• Mutation: Insertion of gene trap vector Vector: UPA
• Mutation details: The gene trap inserted into the promoter 1.2 kb upstream of the transcriptional start site. Reduced gene expression was confirmed. Analysis confirmed reduced protein expression in the colon. (J:229778)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  CMHD-GT_371C12-3	EI698268 ; (MGI Seq Detail)	3' RACE	Chr18:61823189-61825600 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  9 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il17b Mutation: 23 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 2 reference(s)