Adgrl3^{Gt(S17-5H1)Sor}
Gene trapped Allele Detail

Summary

• Symbol: Adgrl3^{Gt(S17-5H1)Sor}
• Name: adhesion G protein-coupled receptor L3; gene trap S17-5H1, Philippe Soriano
• MGI ID: MGI:4973916
• Gene: Adgrl3 Location: Chr5:81167985-81972980 bp, + strand Genetic Position: Chr5, 42.62 cM
• Alliance: Adgrl3^{Gt(S17-5H1)Sor} page

Mutation origin

• Mutant Cell Line: S17-5H1
• Germline Transmission: Earliest citation of germline transmission: J:185872
• Parent Cell Line: AK7.1 (ES Cell)
• Strain of Origin: 129S4/SvJaeSor

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: ROSAFARY
• Mutation details: Trapped gene association determined by genome coordinate overlap and strand. RT-PCR confirmed the absence of transcript expression. (J:185872)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  FHCRC-GT-S17-5H1	CL610430 ; (MGI Seq Detail)	3' RACE	Chr5:81836365-81841502 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  3 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adgrl3 Mutation: 99 strains or lines available

Notes

While genetic variation does not include ADGR13 null mutations in humans, null mice display some phenotypes reminiscent of ADHD and can be utilized as a working model to better understand the function in disease (J:259247).

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 5 reference(s)