Lmna^{Gt(S7-1F1)Sor}
Gene trapped Allele Detail

Summary

• Symbol: Lmna^{Gt(S7-1F1)Sor}
• Name: lamin A; gene trap S7-1F1, Philippe Soriano
• MGI ID: MGI:4974489
• Synonyms: LMNA^GT, LMNA^{Gt(FHCRC-GT-S7-1F1)Sor}
• Gene: Lmna Location: Chr3:88388455-88413842 bp, - strand Genetic Position: Chr3, 38.84 cM
• Alliance: Lmna^{Gt(S7-1F1)Sor} page

Mutation origin

• Mutant Cell Line: S7-1F1
• Germline Transmission: Earliest citation of germline transmission: J:221850
• Parent Cell Line: AK7.1 (ES Cell)
• Strain of Origin: 129S4/SvJaeSor

Mutation description

• Allele Type: Gene trapped (Modified isoform(s), Reporter)
• Mutation: Insertion of gene trap vector Vector: ROSAFARY
• Mutation details: The gene trap vector inserted into intron 2. Western blot analysis confirmed the absence of full-length or truncated A and C isoforms. (J:221850)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  FHCRC-GT-S7-1F1	CG784240 ; (MGI Seq Detail)	3' RACE	Chr3:88392316-88395735 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  92 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:	10 assay results
In Structures Affected by this Mutation:	8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lmna Mutation: 84 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)