Rassf9^{Tg(PDLIM7*)2Cml}
Transgenic Allele Detail

Summary

• Symbol: Rassf9^{Tg(PDLIM7*)2Cml}
• Name: Ras association (RalGDS/AF-6) domain family (N-terminal) member 9; transgene insertion 2, Chiou-Mei Lee
• MGI ID: MGI:4999600
• Gene: Rassf9 Location: Chr10:102348083-102385597 bp, + strand Genetic Position: Chr10, 53.56 cM
• Alliance: Rassf9^{Tg(PDLIM7*)2Cml} page

Small body size and decreased weight of Rassf9^{Tg(PDLIM7*)2Cml}/Rassf9^{Tg(PDLIM7*)2Cml} mice

Show the 6 phenotype image(s) involving this allele.

Transgene origin

• Strain of Origin: ICR

Transgene description

• Transgene Type: Transgenic (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A transgene, which contained the nasopharyngeal carcinoma-derived human gene with upstream promoter, coding sequence, and 3' untranslated region, inserted into intron 1 and resulted in a 7.2 kb deletion from intron 1. Western blot analysis confirmed that the transgene failed to express in skin extracts. The absence of endogenous transcript expression was confirmed by RT-PCR on skin, brain, heart, lung, liver, stomach, intestine, and kidney extracts. (J:171677)

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rassf9 Mutation: 21 strains or lines available

References

• Original: J:171677 Lee CM, et al., A novel role of RASSF9 in maintaining epidermal homeostasis. PLoS One. 2011;6(3):e17867
• All: 1 reference(s)