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Rassf9Tg(PDLIM7*)2Cml
Transgenic Allele Detail
Summary
Symbol: Rassf9Tg(PDLIM7*)2Cml
Name: Ras association (RalGDS/AF-6) domain family (N-terminal) member 9; transgene insertion 2, Chiou-Mei Lee
MGI ID: MGI:4999600
Gene: Rassf9  Location: Chr10:102348083-102385597 bp, + strand  Genetic Position: Chr10, 53.56 cM
Alliance: Rassf9Tg(PDLIM7*)2Cml page
Small body size and decreased weight of Rassf9Tg(PDLIM7*)2Cml/Rassf9Tg(PDLIM7*)2Cml mice

Show the 6 phenotype image(s) involving this allele.

Transgene
origin
Strain of Origin:  ICR
Transgene
description
Transgene Type:    Transgenic (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA transgene, which contained the nasopharyngeal carcinoma-derived human gene with upstream promoter, coding sequence, and 3' untranslated region, inserted into intron 1 and resulted in a 7.2 kb deletion from intron 1. Western blot analysis confirmed that the transgene failed to express in skin extracts. The absence of endogenous transcript expression was confirmed by RT-PCR on skin, brain, heart, lung, liver, stomach, intestine, and kidney extracts. (J:171677)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 7 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rassf9 Mutation:  21 strains or lines available
References
Original:  J:171677 Lee CM, et al., A novel role of RASSF9 in maintaining epidermal homeostasis. PLoS One. 2011;6(3):e17867
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory