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l11Jus74
Chemically induced Allele Detail
Summary
Symbol: l11Jus74
Name: lethal, Chr 11, Justice 74
MGI ID: MGI:4999624
Gene: l11Jus74  Location: unknown  Genetic Position: Chr11, Syntenic
Alliance: l11Jus74 page
Mutation
origin
Strain of Origin:  C57BL/6J
Project Collection: Mutagenesis for Dev. Defects
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsWhole exome sequencing has identified an A to T transversion at Chr 11:77984176 predicted to change amino acid 343 of NEK8 from valine to glutamic acid and an A to T transversion at Chr 11:102258914 predicted to change amino acid 46 of RUNDC3A from tyrosine to phenylalanine. (J:176116)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any l11Jus74 Mutation:  0 strains or lines available
References
Original:  J:176116 Fairfield H, et al., Mutation discovery in mice by whole exome sequencing. Genome Biol. 2011 Sep 14;12(9):R86
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory