Map3k11^m1J
Spontaneous Allele Detail

Summary

• Symbol: Map3k11^m1J
• Name: mitogen-activated protein kinase kinase kinase 11; mutation 1 Jackson
• MGI ID: MGI:4999723
• Synonyms: bloodline
• Gene: Map3k11 Location: Chr19:5738770-5752893 bp, + strand Genetic Position: Chr19, 4.34 cM
• Alliance: Map3k11^m1J page

Red dorsal lines in the skin of Map3k11^m1J/Map3k11^m1J pups (right and center) compared to control (left)

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: STOCK Bdnf^tm3Jae/J

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: A spontaneous G-to-A mutation at position 5,695,295 (GRCm38) changes amino acid 293 from glutamate to lysine (p.E293K). (J:175214, J:176116)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Map3k11 Mutation: 32 strains or lines available

References

• Original: J:175214 Karst SY, et al., A spontaneous point mutation in the Map3k11 gene causes dorsal stripes and necrotic tooth pulp. MGI Direct Data Submission. 2011
• All: 2 reference(s)