Rora^tm1(cre)Ddmo
Targeted Allele Detail

Summary

• Symbol: Rora^tm1(cre)Ddmo
• Name: RAR-related orphan receptor alpha; targeted mutation 1, Dennis D M O'Leary
• MGI ID: MGI:5000017
• Synonyms: RORalpha^Cre
• Gene: Rora Location: Chr9:68561068-69295528 bp, + strand Genetic Position: Chr9, 37.45 cM
• Alliance: Rora^tm1(cre)Ddmo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171771
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Rora^tm1(cre)Ddmo expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Rora (MGI:104661)

• Mutation details: An IRES/cre/FRT/neo/FRT expression cassette was inserted into the 3' noncoding region of the Rora gene. Cre expression is similar to endogenous expression. (J:171771, J:199176)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Rora (mouse) Summary of all recombinase alleles driven by Rora. Alliance mouse Rora gene page

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rora Mutation: 43 strains or lines available

References

• Original: J:171771 Wu CS, et al., Requirement of cannabinoid CB(1) receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections. Eur J Neurosci. 2010 Sep;32(5):693-706
• All: 24 reference(s)