Boctm1Rsk
Targeted Allele Detail
|
Symbol: |
Boctm1Rsk |
Name: |
BOC cell adhesion associated, oncogene regulated; targeted mutation 1, Robert S Krauss |
MGI ID: |
MGI:5000228 |
Synonyms: |
Boc-, BocAP-1 |
Gene: |
Boc Location: Chr16:44305408-44379233 bp, - strand Genetic Position: Chr16, 28.81 cM, cytoband B5
|
Alliance: |
Boctm1Rsk page
|
|
Germline Transmission: |
Earliest citation of germline transmission:
J:171767
|
Parent Cell Line: |
TC1/TC-1 (ES Cell)
|
Strain of Origin: |
129S6/SvEvTac
|
|
Allele Type: |
|
Targeted (Null/knockout, Reporter) |
Mutations: |
|
Insertion, Intragenic deletion
|
|
|
Mutation details: A 540 bp region including the entire first coding exon was deleted and an IRES-hAP and floxed PGK-neo cassette was inserted in exon 2 via homologous recombination. Western blot analysis confirmed the absence of protein expression in homozygous embryos. Alkaline phosphatase activity mirrors endogenous gene expression.
(J:171767)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any Boc Mutation: |
61 strains or lines available
|
|
Original: |
J:171767 Zhang W, et al., Boc modifies the holoprosencephaly spectrum of Cdo mutant mice. Dis Model Mech. 2011 May-Jun;4(3):368-80 |
All: |
4 reference(s) |
|