Tg(Alb-TAg)#Arnd
Transgene Detail

Summary

• Symbol: Tg(Alb-TAg)#Arnd
• Name: transgene insertion, Bernd Arnold
• MGI ID: MGI:5000250
• Synonyms: Alb-SV40TAg(ind), AST
• Transgene: Tg(Alb-TAg)#Arnd Location: unknown
• Alliance: Tg(Alb-TAg)#Arnd page

Transgene origin

• Strain of Origin: (CBA x DBA/2)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The mouse promoter drives hepatocyte-specific expression of the SV40 T antigen preceded by a floxed neo STOP cassette. Removal of the STOP cassette is required to achieve expression of TAg. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:171880)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:171880 Stahl S, et al., Tumor agonist peptides break tolerance and elicit effective CTL responses in an inducible mouse model of hepatocellular carcinoma. Immunol Lett. 2009 Mar 24;123(1):31-7
• All: 6 reference(s)