Tg(AR*100Q)#Als
Transgene Detail

Summary

• Symbol: Tg(AR*100Q)#Als
• Name: transgene insertion, Albert La Spada
• MGI ID: MGI:5000269
• Synonyms: AR100, YAC AR100
• Transgene: Tg(AR*100Q)#Als Location: unknown
• Alliance: Tg(AR*100Q)#Als page

Transgene origin

• Germline Transmission: Earliest citation of germline transmission: J:170487
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(AR*100Q)#Als expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  AR (367)

  Ar	(MGI:88064)

• Mutation details: The transgene contains a human YAC in which the CAG repeat contains 100 repeats (100Q). Lines C25 and C32 were generated. The pound symbol (#) is used when line is not specified and/or lines are pooled. (J:89772)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:170487 Malik B, et al., Absence of disturbed axonal transport in spinal and bulbar muscular atrophy. Hum Mol Genet. 2011 May 1;20(9):1776-86
• All: 7 reference(s)