Tg(SFTPC-rtTA)2Jaw
Transgene Detail
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| Symbol: |
Tg(SFTPC-rtTA)2Jaw |
| Name: |
transgene insertion 2, Jeffrey A Whitsett |
| MGI ID: |
MGI:5000438 |
| Synonyms: |
SP-C-rtTA (line 2) |
| Transgene: |
Tg(SFTPC-rtTA)2Jaw Location: unknown
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| Alliance: |
Tg(SFTPC-rtTA)2Jaw page
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| Strain of Origin: |
129 and C57BL/6
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| Transgene Type: |
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Transgenic (Transactivator) |
| Mutation: |
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Insertion
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Mutation details: The transgene is composed of 3.7 kb of human SFTPC promoter, a reverse tetracycline responsive transactivator gene (rt-TA), and a 0.45 kb SV40 polyadenylation signal. Transgene expression was confirmed by RT-PCR analysis. The human SFTPC promoter is active in respiratory epithelial cells.
(J:61736)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:171151 Chen S, et al., CTGF disrupts alveolarization and induces pulmonary hypertension in neonatal mice: implication in the pathogenesis of severe bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol. 2011 Mar;300(3):L330-40 |
| All: |
6 reference(s) |
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Analysis Tools
