Tg(CD68-RETN)#Laz
Transgene Detail

Summary

• Symbol: Tg(CD68-RETN)#Laz
• Name: transgene insertion, Mitchell A Lazar
• MGI ID: MGI:5000489
• Synonyms: CD68hR
• Transgene: Tg(CD68-RETN)#Laz Location: unknown
• Alliance: Tg(CD68-RETN)#Laz page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The human promoter drives macrophage-specific expression of the human cDNA. Two lines were generated. The pound symbol is used when no line is specified and/or lines are pooled. (J:171262)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:171262 Qatanani M, et al., Macrophage-derived human resistin exacerbates adipose tissue inflammation and insulin resistance in mice. J Clin Invest. 2009 Mar;119(3):531-9
• All: 3 reference(s)