Pdcd10^tm1Wami
Targeted Allele Detail

Summary

• Symbol: Pdcd10^tm1Wami
• Name: programmed cell death 10; targeted mutation 1, Wang Min
• MGI ID: MGI:5002630
• Synonyms: CCM3^loxP, Pdcd10^tm1Wmin
• Gene: Pdcd10 Location: Chr3:75423797-75464159 bp, - strand Genetic Position: Chr3, 33.76 cM, cytoband E3
• Alliance: Pdcd10^tm1Wami page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171969
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129 and C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 4. A floxed neo cassette was inserted downstream of exon 5. (J:171969)

Disease models

Expression

In Structures Affected by this Mutation:

14 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pdcd10 Mutation: 20 strains or lines available

References

• Original: J:171969 He Y, et al., Stabilization of VEGFR2 signaling by cerebral cavernous malformation 3 is critical for vascular development. Sci Signal. 2010;3(116):ra26
• All: 17 reference(s)