Pdcd10^tm1.1Wami
Targeted Allele Detail

Summary

• Symbol: Pdcd10^tm1.1Wami
• Name: programmed cell death 10; targeted mutation 1.1, Wang Min
• MGI ID: MGI:5002631
• Synonyms: Pdcd10^tm1.1Wmin
• Gene: Pdcd10 Location: Chr3:75423797-75464159 bp, - strand Genetic Position: Chr3, 33.76 cM, cytoband E3
• Alliance: Pdcd10^tm1.1Wami page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171969
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129 and C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 4 and 5 were removed by cre-mediated recombination. The absence of protein expression was confirmed by western blot analysis on E8.0 yolk sac extracts. (J:171969)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pdcd10 Mutation: 20 strains or lines available

References

• Original: J:171969 He Y, et al., Stabilization of VEGFR2 signaling by cerebral cavernous malformation 3 is critical for vascular development. Sci Signal. 2010;3(116):ra26
• All: 4 reference(s)