Kpna3^tm1Bdr
Targeted Allele Detail

Summary

• Symbol: Kpna3^tm1Bdr
• Name: karyopherin subunit alpha 3; targeted mutation 1, Michael Bader
• MGI ID: MGI:5004868
• Synonyms: alpha4^-, Kpna4^tm1Bdr
• Gene: Kpna3 Location: Chr14:61602660-61677323 bp, - strand Genetic Position: Chr14, 32.76 cM, cytoband C3
• Alliance: Kpna3^tm1Bdr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171441
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Exons 3 to 6 were replaced with a neo cassette via homologous recombination. (J:171441)

Generation of the Kpna3^tm1Bdr allele

Expression

In Mice Carrying this Mutation:

5 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kpna3 Mutation: 40 strains or lines available

References

• Original: J:171441 Rother F, et al., Importin alpha7 Is Essential for Zygotic Genome Activation and Early Mouse Development. PLoS One. 2011;6(3):e18310
• All: 5 reference(s)