TgTn(pb-sb-GrOnc)#aGsva
Transgene Detail

Summary

• Symbol: TgTn(pb-sb-GrOnc)#aGsva
• Name: transgenic transposon concatemer #a, George S Vassiliou
• MGI ID: MGI:5004883
• Synonyms: GrOnc
• Transgene: TgTn(pb-sb-GrOnc)#aGsva Location: unknown
• Alliance: TgTn(pb-sb-GrOnc)#aGsva page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Transposon concatemer)
• Mutation: Insertion
• Mutation details: Piggybac and sleeping beauty inverted repeats flank (in 5' to 3' order) a Carp beta-actin splice acceptor, bidirectional polyadenylation sequences, the oncogenic murine leukemia virus Graffi GV-1.4 long terminal repeat, the Lun splice donor, and the Engrailed 2 splice acceptor. Line #a contains 80 copies of the transposon concatemer. (J:172071)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:172071 Vassiliou GS, et al., Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice. Nat Genet. 2011 May;43(5):470-5
• All: 2 reference(s)