Tg(Nphs2-RNAi:Gpc5)#Enoi
Transgene Detail

Summary

• Symbol: Tg(Nphs2-RNAi:Gpc5)#Enoi
• Name: transgene insertion, Eisei Noiri
• MGI ID: MGI:5004938
• Synonyms: Gpc5 siRNA
• Transgene: Tg(Nphs2-RNAi:Gpc5)#Enoi Location: unknown
• Alliance: Tg(Nphs2-RNAi:Gpc5)#Enoi page

Transgene origin

• Strain of Origin: C57BL/6 x DBA/2

Transgene description

• Transgene Type: Transgenic (Knockdown)
• Mutation: Insertion
• Tg(Nphs2-RNAi:Gpc5)#Enoi involves 1 genes/genome features (Gpc5) View all
• Mutation details: The promoter drives podocyte-specific expression of one of three short hairpin targeting Gpc5. Reduced protein expression was confirmed by western blot analysis. (J:172070)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:172070 Okamoto K, et al., Common variation in GPC5 is associated with acquired nephrotic syndrome. Nat Genet. 2011 May;43(5):459-63
• All: 2 reference(s)