Tg(Hoxb1-cre)r4Mist
Transgene Detail

Summary

• Symbol: Tg(Hoxb1-cre)r4Mist
• Name: transgene insertion r4, Michele Studer
• MGI ID: MGI:5006714
• Synonyms: b1r4-Cre, R4-CRE, R4::Cre
• Transgene: Tg(Hoxb1-cre)r4Mist Location: unknown
• Alliance: Tg(Hoxb1-cre)r4Mist page

Transgene origin

• Strain of Origin: CD-1

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Hoxb1-cre)r4Mist expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Hoxb1

• Mutation details: This transgene contains the cre recombinase coding sequence and the metallothionein 1 polyadenylation signal between the Wnt1 basic promoter and intron, which is followed by the inverted rhombomere 4 (r4) enhancer and the r3/r5 repressor from the Hoxb1 locus. These elements together restrict expression to rhombomere 4 in the hindbrain of the developing embryo. (J:20433, J:197162)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Hoxb1 (species not specified) Summary of all recombinase alleles driven by Hoxb1.

Expression

In Mice Carrying this Mutation:

2 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:197162 Di Bonito M, et al., Assembly of the auditory circuitry by a Hox genetic network in the mouse brainstem. PLoS Genet. 2013;9(2):e1003249
• All: 9 reference(s)