Cd79a^m1Anu
Chemically induced Allele Detail

Summary

• Symbol: Cd79a^m1Anu
• Name: CD79A antigen (immunoglobulin-associated alpha); mutation 1, The Australian National University
• MGI ID: MGI:5006856
• Synonyms: Cd79a^ken, ENU5WT:054, Kenobi
• Gene: Cd79a Location: Chr7:24596922-24601283 bp, + strand Genetic Position: Chr7, 13.49 cM
• Alliance: Cd79a^m1Anu page

Mutation origin

• Strain of Origin: C57BL/6JSfdAnu
• Project Collection: APF ENU Mutagenesis

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a G to A transition in exon 2, at the position corresponding to nucleotide 327 of the cDNA sequence, that replaces tryptophan with a premature stop codon at amino acid position 62 of the protein (W62Ter). (J:171924)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Cd79a Mutation: 24 strains or lines available

References

• Original: J:171924 Yabas M, et al., ATP11C is critical for the internalization of phosphatidylserine and differentiation of B lymphocytes. Nat Immunol. 2011 May;12(5):441-9
• All: 7 reference(s)