Atp11c^m2Anu
Chemically induced Allele Detail

Summary

• Symbol: Atp11c^m2Anu
• Name: ATPase, class VI, type 11C; mutation 2, The Australian National University
• MGI ID: MGI:5006936
• Synonyms: 18NIH30a, 18NIH30b, ENU18NIH:030b
• Gene: Atp11c Location: ChrX:59268643-59450041 bp, - strand Genetic Position: ChrX, 33.5 cM, cytoband A5
• Alliance: Atp11c^m2Anu page

Mutation origin

• Strain of Origin: C57BL/6JAnu
• Project Collection: APF ENU Mutagenesis

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a point mutation at the second nucleotide of intron 26, replacing an invariant, essential T with G in the consensus splice donor sequence of exon 26. (J:71802, J:171924)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Atp11c Mutation: 16 strains or lines available

References

• Original: J:171924 Yabas M, et al., ATP11C is critical for the internalization of phosphatidylserine and differentiation of B lymphocytes. Nat Immunol. 2011 May;12(5):441-9
• All: 2 reference(s)