Slurp2^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Slurp2^tm1Lex
• Name: secreted Ly6/Plaur domain containing 2; targeted mutation 1, Lexicon Pharmaceuticals
• MGI ID: MGI:5006991
• Gene: Slurp2 Location: Chr15:74614688-74618536 bp, - strand Genetic Position: Chr15, 34.27 cM
• Alliance: Slurp2^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171883
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A 493 bp portion of the coding region, encoded by part of exons 2 and 3, was replaced with loxP site flanked lacZ reporter and neomycin resistance gene cassettes. Absence of transcription from this allele was confirmed by qRT-PCR. (J:171883)

Disease models

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Slurp2 Mutation: 13 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
• All: 3 reference(s)