Vsir^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Vsir^tm1Lex
• Name: V-set immunoregulatory receptor; targeted mutation 1, Lexicon Pharmaceuticals
• MGI ID: MGI:5006997
• Synonyms: PD-1H KO
• Gene: Vsir Location: Chr10:60182630-60208463 bp, + strand Genetic Position: Chr10, 30.26 cM, cytoband B3
• Alliance: Vsir^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171883
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exon 1 was targeted by homologous recombination. (J:171883, J:238034)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Vsir Mutation: 26 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
• All: 19 reference(s)