Acsl5^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Acsl5^tm1Lex
• Name: acyl-CoA synthetase long-chain family member 5; targeted mutation 1, Lexicon Pharmaceuticals
• MGI ID: MGI:5007008
• Gene: Acsl5 Location: Chr19:55240298-55285060 bp, + strand Genetic Position: Chr19, 51.3 cM, cytoband D2
• Alliance: Acsl5^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171883
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A portion of the coding region was targeted by homologous recombination. Coding exons 14 through 16 were targeted (NCBI accession BC031544.1). Disruption of the target gene was confirmed by Southern hybridization analysis. (J:171883)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Acsl5 Mutation: 56 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
• All: 3 reference(s)