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Ccbe1tm1Lex
Targeted Allele Detail
Summary
Symbol: Ccbe1tm1Lex
Name: collagen and calcium binding EGF domains 1; targeted mutation 1, Lexicon Pharmaceuticals
MGI ID: MGI:5007046
Synonyms: Ccbe1lacZ
Gene: Ccbe1  Location: Chr18:66189926-66424909 bp, - strand  Genetic Position: Chr18, 39.13 cM, cytoband E1
Alliance: Ccbe1tm1Lex page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:171883
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThis mutant allele was generated by homologous recombination in embryonic stem cells, with a lacZ cassette replacing the first and second coding exons of the gene. (J:171883, J:186594)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 42 assay results
1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Ccbe1 Mutation:  19 strains or lines available
Notes
See also, data as provided by Lexicon Genetics, Inc.
References
Original:  J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory