Cldn18^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Cldn18^tm1Lex
• Name: claudin 18; targeted mutation 1, Lexicon Pharmaceuticals
• MGI ID: MGI:5007067
• Gene: Cldn18 Location: Chr9:99572849-99599320 bp, - strand Genetic Position: Chr9, 52.0 cM, cytoband E3-F1
• Alliance: Cldn18^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171883
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• A neo cassette replaced exons 2 through 4. (J:196719)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Cldn18 Mutation: 19 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
• All: 8 reference(s)