Angptl8^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Angptl8^tm1Lex
• Name: angiopoietin-like 8; targeted mutation 1, Lexicon Pharmaceuticals
• MGI ID: MGI:5007159
• Synonyms: Rifl^-
• Gene: Angptl8 Location: Chr9:21746806-21748643 bp, + strand Genetic Position: Chr9, 7.9 cM
• Alliance: Angptl8^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171883
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Coding exons 1 through 4 were targeted (NCBI accession BC024408.1). Disruption of the target gene was confirmed by Southern hybridization analysis. (J:171883)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Angptl8 Mutation: 14 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
• All: 6 reference(s)