Gpx8^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Gpx8^tm1Lex
• Name: glutathione peroxidase 8 (putative); targeted mutation 1, Lexicon Pharmaceuticals
• MGI ID: MGI:5007170
• Gene: Gpx8 Location: Chr13:113179287-113182944 bp, - strand Genetic Position: Chr13, 63.93 cM
• Alliance: Gpx8^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171883
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Coding exon 1 was targeted (NCBI accession NM_027127.1). Disruption of the target gene was confirmed by Southern hybridization analysis. (J:171883)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Gpx8 Mutation: 18 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
• All: 3 reference(s)