Il17c^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Il17c^tm1Lex
• Name: interleukin 17C; targeted mutation 1, Lexicon Pharmaceuticals
• MGI ID: MGI:5007186
• Gene: Il17c Location: Chr8:123148759-123150378 bp, + strand Genetic Position: Chr8, 71.03 cM
• Alliance: Il17c^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171883
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exons 2 and 3 were replaced with a neo cassette. qRT-PCR on colon extracts confirmed the absence of transcript expression. (J:178967)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Il17c Mutation: 10 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
• All: 12 reference(s)