Il17re^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Il17re^tm1Lex
• Name: interleukin 17 receptor E; targeted mutation 1, Lexicon Pharmaceuticals
• MGI ID: MGI:5007190
• Gene: Il17re Location: Chr6:113435659-113447719 bp, + strand Genetic Position: Chr6, 52.76 cM
• Alliance: Il17re^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171883
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Intragenic deletion
• Mutation details: Exons 7 through 15 were replaced with a beta-geo and puro cassette. qRT-PCR on ear tissue extracts confirmed the absence of transcript expression. (J:178967)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Il17re Mutation: 36 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
• All: 11 reference(s)