Lrrn1^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Lrrn1^tm1Lex
• Name: leucine rich repeat protein 1, neuronal; targeted mutation 1, Lexicon Pharmaceuticals
• MGI ID: MGI:5007226
• Gene: Lrrn1 Location: Chr6:107506729-107547175 bp, + strand Genetic Position: Chr6, 49.71 cM
• Alliance: Lrrn1^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171883
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: The Lrrn1 gene consists of 2 exons, with the start codon located in exon 2 (NCBI accession NM_008516.1). Exon 2 was targeted by homologous recombination. Disruption of the target gene was confirmed by Southern hybridization analysis. (J:171883)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Lrrn1 Mutation: 44 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
• All: 2 reference(s)