Scn2b^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Scn2b^tm1Lex
• Name: sodium channel, voltage-gated, type II, beta; targeted mutation 1, Lexicon Pharmaceuticals
• MGI ID: MGI:5007314
• Gene: Scn2b Location: Chr9:45029174-45041368 bp, + strand Genetic Position: Chr9, 24.84 cM
• Alliance: Scn2b^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171883
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A portion of the coding region was targeted by homologous recombination. Coding exons 2 through 4 were targeted (NCBI accession XM_134787.2). Disruption of the target gene was confirmed by Southern hybridization analysis. (J:171883)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Scn2b Mutation: 14 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
• All: 2 reference(s)