Slc29a3^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Slc29a3^tm1Lex
• Name: solute carrier family 29 (nucleoside transporters), member 3; targeted mutation 1, Lexicon Pharmaceuticals
• MGI ID: MGI:5007332
• Gene: Slc29a3 Location: Chr10:60547851-60588573 bp, - strand Genetic Position: Chr10, 31.38 cM, cytoband B4
• Alliance: Slc29a3^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171883
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 1 and 2 were replaced with a beta-geo/Puro cassette. Western blot analysis confirmed the absence of protein expression in bone marrow-derived macrophages. (J:171883)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Slc29a3 Mutation: 27 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
• All: 7 reference(s)