Slc39a14^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Slc39a14^tm1Lex
• Name: solute carrier family 39 (zinc transporter), member 14; targeted mutation 1, Lexicon Pharmaceuticals
• MGI ID: MGI:5007337
• Synonyms: Zip14^-
• Gene: Slc39a14 Location: Chr14:70540918-70588874 bp, - strand Genetic Position: Chr14, 36.32 cM
• Alliance: Slc39a14^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171883
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exons 3 through 5 (or the first through third coding exon) were targeted. Western blot analysis of tissue lysates confirmed the absence of protein expression in intestine and liver tissues from homozygous mutant mice. (J:171883, J:236296)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Slc39a14 Mutation: 69 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
• All: 16 reference(s)