Susd4^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Susd4^tm1Lex
• Name: sushi domain containing 4; targeted mutation 1, Lexicon Pharmaceuticals
• MGI ID: MGI:5007355
• Gene: Susd4 Location: Chr1:182591609-182724161 bp, + strand Genetic Position: Chr1, 85.94 cM
• Alliance: Susd4^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171883
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: The Susd4 coding exon 1 and preceding sequence was targeted by homologous recombination. qPCR analysis confirmed the absence of mRNA expression in brain tissue from homozygous mutant mice. (J:171883, J:306852)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Susd4 Mutation: 28 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
• All: 4 reference(s)