Sbds^tm1Aljw
Targeted Allele Detail

Summary

• Symbol: Sbds^tm1Aljw
• Name: SBDS ribosome maturation factor; targeted mutation 1, Alan J Warren
• MGI ID: MGI:5007534
• Synonyms: Sbds^fl
• Gene: Sbds Location: Chr5:130274573-130284371 bp, - strand Genetic Position: Chr5, 68.97 cM
• Alliance: Sbds^tm1Aljw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171416
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2. A neo cassette with a 3' loxP site was inserted downstream of exon 2. (J:171416)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sbds Mutation: 31 strains or lines available

References

• Original: J:171416 Finch AJ, et al., Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome. Genes Dev. 2011 May 1;25(9):917-29
• All: 1 reference(s)