Tg(Fabp4-TLE3)#aPton
Transgene Detail

Summary

• Symbol: Tg(Fabp4-TLE3)#aPton
• Name: transgene insertion #a, Peter Tontonoz
• MGI ID: MGI:5007704
• Synonyms: aP2-TLE3
• Transgene: Tg(Fabp4-TLE3)#aPton Location: unknown
• Alliance: Tg(Fabp4-TLE3)#aPton page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Fabp4-TLE3)#aPton expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  TLE3 (7090)

  Tle3	(MGI:104634)

• Mutation details: The promoter drives adipose-specific expression of the human cDNA. At least two lines were generated (aP2-TLE3 and aP2-TLE3-B). The pound symbol (#a) is used to denote the unnamed (aP2-TLE3) line. (J:172245)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:172245 Villanueva CJ, et al., TLE3 is a dual-function transcriptional coregulator of adipogenesis. Cell Metab. 2011 Apr 6;13(4):413-27
• All: 2 reference(s)