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Pi4katm1.1Arte
Targeted Allele Detail
Summary
Symbol: Pi4katm1.1Arte
Name: phosphatidylinositol 4-kinase alpha; targeted mutation 1.1, TaconicArtemis
MGI ID: MGI:5008156
Synonyms: Pi4kaflox
Gene: Pi4ka  Location: Chr16:17098215-17224178 bp, - strand  Genetic Position: Chr16, 10.71 cM
Alliance: Pi4katm1.1Arte page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:172497
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6NTac
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA targeting vector was designed to insert a loxP site followed by a frt-flanked neomycin (neo) resistance cassette upstream of exon 46, and a second loxP site downstream of exon 52 of the phosphatidylinositol 4-kinase, catalytic, alpha polypeptide (Pi4ka) gene. Flp-mediated recombination removed the neo cassette. (J:172497)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pi4ka Mutation:  126 strains or lines available
References
Original:  J:172497 TaconicArtemis, Direct Data Submission 2011/06/17. MGI Direct Data Submission. 2011;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory