Stim2^tm1.1Kuro
Targeted Allele Detail

Summary

• Symbol: Stim2^tm1.1Kuro
• Name: stromal interaction molecule 2; targeted mutation 1.1, Tomohiro Kurosaki
• MGI ID: MGI:5008479
• Synonyms: Stim2^f
• Gene: Stim2 Location: Chr5:54155865-54278399 bp, + strand Genetic Position: Chr5, 29.69 cM
• Alliance: Stim2^tm1.1Kuro page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:172608
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A floxed neo cassette was inserted upstream of exon 6. An additional loxP site was inserted downstream of exon 7. Cre-mediated recombination removed the neo cassette and left exons 6 and 7 floxed. (J:172608)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stim2 Mutation: 42 strains or lines available

References

• Original: J:172608 Matsumoto M, et al., The Calcium Sensors STIM1 and STIM2 Control B Cell Regulatory Function through Interleukin-10 Production. Immunity. 2011 May 27;34(5):703-14
• All: 4 reference(s)