Tg(Sox9-cre/ERT2)1Msan
Transgene Detail

Summary

• Symbol: Tg(Sox9-cre/ERT2)1Msan
• Name: transgene insertion 1, Maike Sander
• MGI ID: MGI:5009223
• Synonyms: Sox9CreER, Sox9CreER^T2
• Transgene: Tg(Sox9-cre/ERT2)1Msan Location: unknown
• Alliance: Tg(Sox9-cre/ERT2)1Msan page

Transgene origin

• Strain of Origin: (BALB/c x C57BL/6)F2

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Sox9-cre/ERT2)1Msan expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Sox9 (MGI:98371)

• Mutation details: BAC RP23-229L12 was modified by inserting a Kozak-cre/ERT2-polyA in place of the ATG codon in exon 1 of the Sox9 open reading frame. The purified construct was injected into the pronuclei of fertilized CB6F2 oocytes. (J:170126)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Sox9 (mouse) Summary of all recombinase alleles driven by Sox9. Comparative matrix view of recombinase activities Alliance mouse Sox9 gene page

Tumor Data

List all tumor models in MMHCdb carrying Tg(Sox9-cre/ERT2)1Msan

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:170126 Kopp JL, et al., Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas. Development. 2011 Feb;138(4):653-65
• All: 62 reference(s)