Atg3^tm1.1Ywh
Targeted Allele Detail

Summary

• Symbol: Atg3^tm1.1Ywh
• Name: autophagy related 3; targeted mutation 1.1, You-Wen He
• MGI ID: MGI:5009305
• Synonyms: Atg3^f
• Gene: Atg3 Location: Chr16:44979192-45008901 bp, + strand Genetic Position: Chr16, 29.45 cM, cytoband B5
• Alliance: Atg3^tm1.1Ywh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:172749
• Parent Cell Line: EF1 (ES Cell)
• Strain of Origin: 129S/SvEv x C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 8. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 10. Flp-mediated recombination removed the neo cassette and left exons 8 through 10 floxed. (J:172749)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atg3 Mutation: 19 strains or lines available

References

• Original: J:172749 Jia W, et al., Temporal regulation of intracellular organelle homeostasis in T lymphocytes by autophagy. J Immunol. 2011 May 1;186(9):5313-22
• All: 13 reference(s)